Flu facilitate overgrowth of pneumonia bacteria

Influenza, viral infection consisting of a medical condition characterized by fever, cough, headache and body pain, complicated by a bacterial pneumonia, leading to the development of breakthrough very dangerous.

A study conducted by the joint venture by the scientists from the Center for Infection Research in Braunschweig, the University Otto - von - Guericke and the Karolinska Institute in Sweden examined the link between influenza infections and pneumonia.

Some viral infections lead to a so-called lymphopenia (decreased below normal levels of lymphocytes circulating valorem), the reason for this decline remains unknown. The researchers inoculated guinea pigs with influenza virus and measured their daily plasma lymphocytes. On some days, infected mice were exposed to doses of bacteria causing pneumonia, the dose usually has no noticeable effect on healthy people are quickly countered by the immune system. Previously inoculated mice developed an overgrowth influenza pneumonia and died, but surprisingly, biological samples did not show a lymphopenia.

Previously healthy mice (neinoculati influenza virus) have kept the state of health.To discover if a drop in immune cells favors a bacteria infection, pneumonia, some healthy mice received an immunosuppressive agent inducandu lymphopenia being iatrogenic. Then were exposed bacteria pneumonia, but despite limfopeniei, mice and completely recovered.

With these results, researchers were able to demonstrate that facilitates and enhances a flu infection, pneumonia, infirmand assumption that this is caused by a drop in immune cells. Researchers hypothesis is that the phenomenon observed is the result of the host immune system function. It inhibits, through a negative feedback, anti-influenza overactive immune cells not to cause healthy lung tissue autolyzer a decrease in the number of elements and system functions monocito - macrophages. Ultrastructural phenomena can occur as a weight loss of barrier function of airway mucosal cell membrane. The combination of these two phenomena histoire-physiological result in the possibility of development of bacterial cultures. The results obtained on animal models are the reference for the occurrence of similar situations in humans.  The study is among the first that sense it realtà between influenza and pneumonia, and therefore further studies must verify whether the model is viable and discovered the disease process is repeated.

With this so called "pigflu or pig influenza"" and the winter approach is better to know and to be protected.